Principal Scientist

  • Full Time (PhD/MD)
  • Anywhere

DxLab Inc. (DxLab)

DxLab Inc. (DxLab) is a venture-backed biotech startup, spun out of MIT and Harvard, developing and commercializing next-generation point-of-care (POC) diagnostics systems for rapid and low-cost detection of various diseases and health conditions. Combining proprietary platform technology with novel target detection and signal processing methods, we are advancing a pipeline of rapid POC tests for different pathogens and biomarkers.

We are seeking a highly motivated and skilled scientist to lead the development of our in vitro diagnostics (IVD) assays, from the feasibility stage to clinical studies to regulatory submissions/approvals. The Principal Scientist will be in charge of designing and optimizing new assay formulations, primers, and reaction conditions. The Principal Scientist will also support external CRO/CMO management, which includes communicating with the project managers at CRO/CMOs to review data, plan future studies/manufacturing, and optimize their processes to fit our needs. This position offers an opportunity to work broadly across various functions at DxLab that include clinical studies, quality management/quality assurance, regulatory submissions, manufacturing, and business development.

Key Responsibilities

  • Develop and optimize new assays for target oligonucleotide detection to support
    the development of new IVD tests
  • Evaluate performance of new assays and IVD tests using key performance metrics
  • Lead in silico analyses for inclusivity and cross-reactivity assessment
  • Supervise the work of junior scientists and research associates
  • Manage external CRO/CMOs to carry out new studies, schedule production, procure critical components, and complete QC activities
  • Support grant applications, clinical studies, and regulatory submission
  • Develop inspection and QC plans and criteria for key reagents and processes
  • Prepare and deliver scientific presentations for internal meetings

Qualifications

  • Ph.D. in molecular biology, biological engineering, chemical engineering, or other related science/engineering field
  • Extensive hands-on experience with PCR and/or LAMP assays; experience with molecular diagnostics assay development and/or manufacturing is a plus
  • Expertise in genomic sequence analysis; experience with primer design is highly preferred
  • Experience with grant writing is a plus
  • Strong interpersonal and communication (verbal and writing) skills
  • Time management skills and ability to meet tight deadlines

To apply, send a resume/CV to support@dxlab.bio or visit https://www.dxlab.bio/join-the-team .

DxLab is an equal opportunity employer and values different experiences and ways of thinking.

To apply for this job please visit www.dxlab.bio.